tag:blogger.com,1999:blog-8353442983052145851.post8388096430445037922..comments2024-03-14T18:26:18.208-07:00Comments on autism's gadfly: could Yuri Danilov help me and other ASD sufferers?jonathanhttp://www.blogger.com/profile/14972394536850151087noreply@blogger.comBlogger16125tag:blogger.com,1999:blog-8353442983052145851.post-7559114669393688072013-10-30T07:54:09.725-07:002013-10-30T07:54:09.725-07:00@Kenneth, don't know the answer to that, you&#...@Kenneth, don't know the answer to that, you'll have to contact Dr. Danilovjonathanhttps://www.blogger.com/profile/14972394536850151087noreply@blogger.comtag:blogger.com,1999:blog-8353442983052145851.post-36726272361637164762013-10-29T22:05:32.083-07:002013-10-29T22:05:32.083-07:00I just recently bumped to this blog post while I w...I just recently bumped to this blog post while I was researching about Arizona Retinal Specialists. I find what you wrote intriguing, so I researched about it, but it seems no recent article (2013) are speaking of this treatment anymore. So what has become of this device? Did it work?Anonymoushttps://www.blogger.com/profile/11567936051101434074noreply@blogger.comtag:blogger.com,1999:blog-8353442983052145851.post-24706486768575265662010-07-14T14:50:37.240-07:002010-07-14T14:50:37.240-07:00The link AoA provided is goes to a deleted page an...The link AoA provided is goes to a deleted page and is apparently outdated, which is why I also provided the direct link to the same ARI article AoA linked to, and that works.Jake Crosbyhttp://www.ageofautism.com/jake-crosbynoreply@blogger.comtag:blogger.com,1999:blog-8353442983052145851.post-91638892339010898402010-07-13T17:13:12.168-07:002010-07-13T17:13:12.168-07:00i can't tell jake. What you gave me is a link...i can't tell jake. What you gave me is a link that goes to an article that was deleted by ARI apparently. I am not sure if it is the same thing that I read about two years ago or not. I can't really tell. I just remember what Edelson said, he did not say anything about a sub group. The quote you have given me about the chronic diarrhea is from something else and has nothing to do with the article that was on AoA where they misrepresented the facts. But I am not going to get into an endless argument.jonathanhttps://www.blogger.com/profile/14972394536850151087noreply@blogger.comtag:blogger.com,1999:blog-8353442983052145851.post-84559631426126643382010-07-13T17:01:57.061-07:002010-07-13T17:01:57.061-07:00Jonathan, again, I will quote to you Dr. Edelson&#...Jonathan, again, I will quote to you Dr. Edelson's own conclusion in the article you cite, where he states:<br /><br />"ARI would very much like to fund controlled studies investigating the effects of porcine secretin on autistic individuals suffering from chronic diarrhea. If you are a researcher and/or know of a top-notch researcher who is interested in continuing this line of research, please write to us at Secretin @ Autism.com."<br />http://legacy.autism.com/treatable/drug/secretin_org.htm<br /><br />He is explicitly referring to people with gastrointestinal problems as a subgroup that can be benefited by secretin, NOT all autistic people.<br /><br />And does this look like his article was posted in full?<br />http://www.ageofautism.com/2008/08/autism-research.html<br /><br />Neither ARI nor AoA misrepresented Dr. Kern's study.Jake Crosbyhttp://www.ageofautism.com/jake-crosbynoreply@blogger.comtag:blogger.com,1999:blog-8353442983052145851.post-41535447601723383602010-07-13T16:13:02.189-07:002010-07-13T16:13:02.189-07:00Jake, if a external rubbing lotion helped autism, ...Jake, if a external rubbing lotion helped autism, it would be front page news. <br /><br />"It also failed to supplement for essential nutrients lost - as is done in clinical treatment with chelation. " I'm not sure how you know this, but I'll assume you have some sort of proof to back up that accusation. However:<br /><br />I'm sorry, but I won't subject my child to possible brain damage based on Jake Crosby's recommended protocol nor these feral "doctors" who are so far outside the mainstream and who make a point to remind their flock that they are persecuted for their beliefs. <br /><br />By the way, autism continues to climb while AoA folks continue to cling to old belief structures.Kent Adamsnoreply@blogger.comtag:blogger.com,1999:blog-8353442983052145851.post-81470126212193702872010-07-13T16:04:17.658-07:002010-07-13T16:04:17.658-07:00No, they published the post int its entirety. The...No, they published the post int its entirety. The copy of the post was originally on ARI's website was published on AoA. Edelson (and AoA by extension) cited Kern's study as something that could potentially help all autistic people. They did not mention that her findings were just a small percentage of the subjects of the study and all of these had gastrointestinal issues. Edelson misrepresented Kern's study and someone who had not read the study as I had would get the idea that the results could be applicable to someone not within the subset of Kern's findings. <br /><br />Since AoA published the post and did not specify Edelson's factual errors or misrepresentation, they misrepresented the study also.jonathanhttps://www.blogger.com/profile/14972394536850151087noreply@blogger.comtag:blogger.com,1999:blog-8353442983052145851.post-11766521494622364072010-07-13T15:09:39.227-07:002010-07-13T15:09:39.227-07:00"yet the internal review board of the study i..."yet the internal review board of the study is the university of naturopathic medicine rather than a more conventional review board at arizona state university or Tulane university which could have provided a review board. This in itself makes the study somewhat suspect."<br /><br />-That changes nothing, all IRBs are charged with conforming to the same FDA rules and guidelines that apply. In this case, it's probably because of the IRB's affiliation with the institution of the lead researcher - James Adams - that the IRB for this study was chosen as it was.<br /><br />"Also, the techniques used to assess functioning levels after chelation except for the ADOS are nonstandard tests just prepared by B. Rimland and Steven Edelson"<br /><br />Wrong, only one is, and personally I would consider it a huge plus that a research diagnostic tool was created by ARI, especially Dr. Bernie Rimland, but that's just me...<br /><br />"ADOS is not used to measure severity level, so this was another problem."<br /><br />It is:<br /><br />"This metric should be useful in comparing assessments across modules and time, and identifying trajectories of autism severity for clinical, genetic, and neurobiological research." <br />http://www.springerlink.com/content/f84020m52p74l1k7/Jake Crosbyhttp://www.ageofautism.com/jake-crosbynoreply@blogger.comtag:blogger.com,1999:blog-8353442983052145851.post-2961764712745275902010-07-13T15:02:35.842-07:002010-07-13T15:02:35.842-07:00"Jake, give a link to real md's in a resp..."Jake, give a link to real md's in a respected journal and that would be worth reading."<br /><br />Co-authors Sanford Newmark, Jeffrey Bradstreet and Jane el-Dahr are all "real MDs."'<br /><br />BMC Clinical Pharmacology's unofficial impact factor is 1.88, which is in the upper-middle range - and perfectly respectable especially for a specialist medical journal.Jake Crosbyhttp://www.ageofautism.com/jake-crosbynoreply@blogger.comtag:blogger.com,1999:blog-8353442983052145851.post-55896677738178233812010-07-13T14:42:41.950-07:002010-07-13T14:42:41.950-07:00"Cornel University found that chelation in th..."Cornel University found that chelation in the absence of acute lead poisoning caused brain damage in mice."<br /><br />It also failed to supplement for essential nutrients lost - as is done in clinical treatment with chelation. Lack of supplementation is where these problems arise, so applying the results of that study to real-life chelation is worthless.Jake Crosbyhttp://www.ageofautism.com/jake-crosbynoreply@blogger.comtag:blogger.com,1999:blog-8353442983052145851.post-73569197724287713202010-07-13T14:39:23.803-07:002010-07-13T14:39:23.803-07:00Jonathan, AoA did not publishe the post, just the ...Jonathan, AoA did not publishe the post, just the first introductory paragraph of it saying that the efficacy on secretin has been misreported. We primarily linked to it. In the full post, which is on the ARI website, Dr. Edelson clearly focuses on those of us suffering from chronic diarrhea, for whom secretin was found to be clinically effective:<br /><br />"ARI would very much like to fund controlled studies investigating the effects of porcine secretin on autistic individuals suffering from chronic diarrhea. If you are a researcher and/or know of a top-notch researcher who is interested in continuing this line of research, please write to us at Secretin @ Autism.com."<br />http://legacy.autism.com/treatable/drug/secretin_org.htmJake Crosbyhttp://www.ageofautism.com/jake-crosbynoreply@blogger.comtag:blogger.com,1999:blog-8353442983052145851.post-71260422110737646442010-07-11T07:58:31.241-07:002010-07-11T07:58:31.241-07:00Kent. I read some of the study and James Adams is...Kent. I read some of the study and James Adams is listed as on the faculty of natropathic medicine yet is a professor of materials science at arizona state university. Jane El Dahr is a professor of pediatrics at Tulane, yet the internal review board of the study is the university of naturopathic medicine rather than a more conventional review board at arizona state university or Tulane university which could have provided a review board. This in itself makes the study somewhat suspect. Also, the techniques used to assess functioning levels after chelation except for the ADOS are nonstandard tests just prepared by B. Rimland and Steven Edelson and the ADOS is not used to measure severity level, so this was another problem.jonathanhttps://www.blogger.com/profile/14972394536850151087noreply@blogger.comtag:blogger.com,1999:blog-8353442983052145851.post-62815235295706918872010-07-11T01:49:14.314-07:002010-07-11T01:49:14.314-07:00The first link from Crosby on chelation was done b...The first link from Crosby on chelation was done by naturialpathic researches. They're not qualified to do such a study. I didn't bother to read the rest because I suspect the rest of the links could be as useless as this one was. Jake, give a link to real md's in a respected journal and that would be worth reading.Kent Adamsnoreply@blogger.comtag:blogger.com,1999:blog-8353442983052145851.post-56228307850507597322010-07-11T01:42:57.459-07:002010-07-11T01:42:57.459-07:00Cornel University found that chelation in the abse...Cornel University found that chelation in the absence of acute lead poisoning caused brain damage in mice. If the mice had acute lead poisoning, there was no brain damage. These affects were a byproduct of the study, not what the study was meant to study which to me is more powerful evidence than if a researcher was out to prove a hypothesis.Kent Adamsnoreply@blogger.comtag:blogger.com,1999:blog-8353442983052145851.post-28101336161135642892010-07-10T22:50:02.550-07:002010-07-10T22:50:02.550-07:00Kern only found secretin effective in a minority o...Kern only found secretin effective in a minority of patients, those with gastrointestinal impairments. Edelson wrote a very misleading post which the age of autism published which did not state this fact and made out like secretin was something that could be used for any person with autism regardless of GI problems. Every other study that has looked at secretin has found it is no more effective than saline, though I guess there was one study, forgot who did it that was just a conference presentation and not actually published in a peer reviewed journal by someone in arizona. I do seem to remember gfc diets were studied and found not to be effective. <br /><br />I did not know about chelation and hyperbaric oxygen I will have to look at those references.jonathanhttps://www.blogger.com/profile/14972394536850151087noreply@blogger.comtag:blogger.com,1999:blog-8353442983052145851.post-87594869617441664822010-07-10T21:16:27.181-07:002010-07-10T21:16:27.181-07:00"non peer reviewed treatments such as chelati..."non peer reviewed treatments such as chelation"<br /><br />Wrong.<br />http://www.biomedcentral.com/1472-6904/9/16<br />http://www.biomedcentral.com/1472-6904/9/17<br /><br />"hyperbaric oxygen"<br /><br />False.<br />http://www.biomedcentral.com/1471-2431/9/21<br /><br />"gluten free diets"<br /><br />Incorrect:<br />http://www.ncbi.nlm.nih.gov/pubmed/20406576<br /><br />"Rimland's heir apparent, Steve Edelson, has been trying to bring back research into secretin in spite of study after study refuting its effectiveness."<br /><br />What about the study by Kern et al. - the only study that used the right kind of secretin while successfully identifying a subgroup for whom it would be beneficial that did show it to be effective? You wrote about it!<br />http://autismgadfly.blogspot.com/2008/08/is-secretin-effective-treatment-for.htmlJake Crosbyhttp://www.ageofautism.com/jake-crosbynoreply@blogger.com